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Title: Frontiers of Biotechnology & Pharmaceuticals, Vol. 2 by Huang Zhen, Guo Ming, John Reiner, Kang Zhao ISBN: 7-03-009360-7 Publisher: Science Pr Pub. Date: 01 July, 2001 Format: Hardcover List Price(USD): $98.00

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Average Customer Rating: 5 (4 reviews)

Rating: 5
Summary: contents of vol. 4 for this book
Comment: Contents of Vol. 4

I. Antiviral Research

1.SARS Outbreak and the Diagnostic Technology by Anna M. Zhou (p1-14)
2.SARS Differential Diagnosis with a Bead Array Method by Xu Ma, ZhaoHui Wang, Lisa Varnavas, Christy Teng-Renzelman, Jessie He, ChiungMei Lu, and Jian Han (p15-29)
3.Design of Rhinovirus Protease Inhibitors for Treatment of the Common Cold by Q. May Wang and Shu-Hui Chen (p30-49)
4.Blocking HIV Entry: Discovery and Development of Orally Bioavailable CCR5 Antagonists as Potent Inhibitors of HIV Infection by Ruo W. Steensma (p50-73)
5.Nucleoside and Nucleotide Analogs with Therapeutic Potentials for the Treatment of HBV Infection by Tianwei Ma, Yvonne YeeMai Yip, and Shu-Hui Chen (p74-122)
6.HCV Protease Inhibitors as Potential Therapeutic Agents for the Treatment of HCV Infection by Seng-Lai Tan, Frantz Victor, and Shu-Hui Chen (p123-146)
7.Antiviral Agents for Treatment of Herpes by Jian Eric Hong (p147-180)

II. Biotechnology and Drug Discovery

1.SUMO: The Proteome¡¯s Little Prince by Kosi Gramatikoff, Chun Wu, Xinying Shi, and Fang Fang (p181-210)
2.Genes Associated with Memory Deficit and Brain Aging by Bing Mei and Yinghe Hu (p211-221)
3.Polyclonal Gene-Specific IgY Antibodies for Proteomics and Abundant Plasma Protein Depletion by Xiangming Fang, Kena W. Curran, Lei Huang, Weiping Xiao, William Strauss, Gulia Harvie, Jerald Feitelson, and Wei-Wei Zhang (p222-245)
4.Use of a-Helix Mimicking Templates for Modulating Protein-Protein Interactions by Justin T. Ernst and Hiroshi Nakanishi (p246-278)
5.Identification of Novel a-Helix Secondary Structure Mimetics by Vincent J. Huber, Min S. Lee, and Hiroshi Nakanishi (p279-294)
6.Targeting Specific Amino Acid Residues in Designing Selective Protein Kinase Inhibitors by Yi Liu and Nathanael Gray (p295-313)
7.RNA Directed Small Molecule Drug Discovery by Baogen Wu and Yun He (p314-337)
8.NMR in Drug Discovery by Xuemei Huang and Min S. Lee (p338-349)
9.FDA New Drug Approvals in 2002 by Boying Guo, Ru Bi, Kang Zhao, and John Reiner (p350-360)

Rating: 5
Summary: contents of vol. 3 for this book
Comment: Content of vol.3

I. Biotechnology

1.Ab initio Prediction is not Enough: the Importance of ESTs, Microarrays, and other Genomes in Analyzing the Draft Sequence of the Human Genome by Jeffrey Yuan and Richard Blevins (p1-28)
2.Clinical Applications of Oncogenes and Oncoproteins: HER 2/neu and EGFR as New Therapeutic Targets by Anna M. Zhou and Walter P. Carney (p29-45)
3.Roles of Matrix Metalloproteinases in Developmental and Pathological Processes by Yun-Bo Shi (p46-57)

4.Pharmacogenetic Application of High-Throughput Mutation Detection and Genotyping Technologies by Michael M. Shi (p58-70)
5.Live Salmonella as an Antitumor Agent and Tumor-Selective Protein Delivery Vector by Ming Feng, Xiang Luo, Zujun Lin, Ivan King, and Li-mou Zheng (p71-84)
6.Dynamic Target-Driven Combinatorial Chemistry by Wenbao Li and Bing Yan (p85-95)

II. Drug Discovery

1.Inhibitors of Tumor Necrosis Factor (TNF) Production and Signaling as Antiinflammatory Therapies by Shao-Hui Zhang (p96-109)
2.Calcium Signaling, Store-Operated Channels and Drug Discovery by Jian Li (p110-124)
3.ATP-Competitive Inhibitors of Cyclin-Dependent Kinases by Apos Dermatakis (p125-156)
4.Discovery of a Novel C-4 Modified 2nd Generation Paclitaxel Analog BMS-188797 by Shu-Hui Chen (p157-171)
5.Structure Activity Relationships of Cryptophycins, A Novel Class of Antitumor Antimitotic Agents by Tiechao Li and Chuan Shih (p172-192)
6.Novel Approaches to the Synthesis of Cryptophycin and Related Depsipeptides by Jian Hong and Lianshan Zhang (p193-213)
7.Antifungal Sponge Metabolites by Hong-yu Li (p214-228)
8.The Papulacandin Class of Antifungals by Stephen A. Hitchcock (p229-242)
9.N-Acyl Prodrugs and 3-Amido Pseudomycin Analogs are Effective and Safe Agents against Systemic Fungal Infections by Shu-Hui Chen, Williams Current, and Michael Rodriguez (p243-269)

III. Drug Development

1.Major Factors Influencing Peptide Drug Absorption by Chao Han, Siming Liu, and Binghe Wang (p270-290)
2.Prodrug Derivatization as a Means to Enhance the Delivery of Peptide and Peptidomimetic Drugs by Siming Liu, Chao Han, and Binghe Wang (p291-310)
3.Solid Form Selection in Drug Development by Zhenping Wu, Jia Liu, David Stirling (p311-324)
4.Asymmetric Organozinc Additions Catalyzed by Polybinaphthyls by Lin Pu (p325-336)
5.Chinese Herbal Drugs for Diabetes by Wei Jia, Victoria J. K. Liu, Lida Tang (p337-358)
6.Quality Control of Traditional Chinese Medicine by Wen-Yuan Gao, Hong-Quan Duan, and Pei-Gen Xiao (p359-376)
7.Quantitative Analysis of Azimilide and One of its Metabolites in Mouse Blood by HPLC with UV Detection by James J. Bao (p377-399)
8.FDA New Approvals in 2001 by Kang Zhao, Lan He, and John Reiner (p400-413)

Rating: 5
Summary: contents of vol. 2 for this book
Comment: Content of vol.2

I. Biotechnology

1.Functional Genomics by Yang Pan (p1-8)
2.In vitro Selection of Ligand-binding and Catalytic RNA and DNA by Zhen Huang and Jun Zhao (p9-31)
3.Phage Display: A Powerful Tool in Biomedical Research by Zhihong Guo (p32-58)
4.Advancement of Automation and Biotechnology in the Clinical Laboratory: Blood Gas, Chemiluminescence Immunoassay, and Nucleic Acid Diagnostics by Anna M. Zhou (p59-77)
5.Advantages of Replacing the Total PSA Assay with a Complexed PSA Assay for the Screening and Monitoring of Prostate Cancer by Z. Zhou and P. C. Ng (p78-84)

II. Drug Development

1.Recent Advances in Organic Chemistry Related to Process Research and Development by Ming Guo, Qingping Tian, and Junhua Tao (p85-106)
2.The Impact of Organic Chemistry on Process Research and Development by Dong-Wei Cai, Cheng-Yi Chen and Yao-Jun Shi (p107-138)
3.A Commercial Process for the Synthesis of Corticosteroid 9,11beta-Epoxides by Xiaoyong Fu (p139-156)

4.Application of Biocatalysis in the Pharmaceutical Industry by Junhua Tao, Ming Guo, and Qingping Tian (157-175)
5.Determination of Physicochemical Properties in Drug Discovery and Development by Zhenping Wu, Jia Liu, and Dave Stirling (176-188)
6.Advances in Drug Delivery and Formulation Technologies by Shihong Li (p189-201)
7.Analytical Chemistry in Antisense Oligonucleotide Drug Development by Danhua Chen (p202-224)

III. Pharmaceuticals

1.Therapeutic Targets in the Protein Tyrosine Phosphatase (PTP) Super Family: PTP1B Antagonists for Obesity and Diabetes by Shao-Hui Zhang (p225-244)
2.The Ubiquitin-Mediated Proteolytic Pathway: An Emerging Drug Discovery Target by Weilin Xie, Frank Mercurio, and Kang Zhao (p245-255)
3.Current Developments in Biological Methylations by Zhaohui S. Zhou, Gang Zhao, and Wei Wan (p256-274)
4.Potential Drug Therapies for Lysosomal Storage Disorders by Jian-Qiang Fan (p275-291)
5.Therapeutic Approaches to Cocaine Addiction by Ginger X. Yang (p292-306)
6.Synthesis and Evaluation of L-Fd4C and its Related Nucleoside Analogs as Novel Antiviral Agents by Shu-Hui Chen (p307-328)
7.FDA New Drug Approvals in 2000 by Kang Zhao, John Reiner, and Weilin Xie (p329-349)