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Title: The Lac Operon: A Short History of a Genetic Paradigm by Benno Muller-Hill ISBN: 3-11-014830-7 Publisher: Walter de Gruyter, Inc. Pub. Date: September, 1996 Format: Paperback Volumes: 1 List Price(USD): $38.95 |
Average Customer Rating: 5 (2 reviews)
Rating: 5
Summary: A short review of a short history
Comment: This book is like Ptashne's "Genetic switch" but more personal and at a higher scientific/intellectual level (read "Genetic Switch" first if you have no idea what it is). "The lac Operon" is annotated with many short, colourful, 'behind-the-scenes' anecdotes about the people who were (are) doing the science. These anecdotes, and other historical facts, do an outstanding job of placing the research questions of the time (the answers to which are today taken as 'self-evident truths') in context.
Rating: 5
Summary: The lac Operon, a Paradigm of Beauty and Efficiency
Comment: In "The lac Operon - A Short History of a Genetic Paradigm", Benno Mueller-Hill does an excellent job of describing the history, mistakes, and present-day view of the lac operon. I found it an enjoyable read. The book is written at a level that assumes the reader already knows a bit about molecular biology, and starts with "A Short History of the lac System from its Beginning to 1978". I found the middle section most interesting, where the mistaken interpretations of the lac operon are considered. This would be a very educational read for students (and post-docs and researchers) in the field. Finally, the last section discusses the current model for how the lac Operon works; this model has not made it to many of the undergraduate molecular biology / Genetics textbooks yet. Overall I was quite happy with this short book on the first bacterial operon to be characterised.
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Title: Genetic Switch: Phage Lambda and Higher Organisms by Mark Ptashne ISBN: 0865422095 Publisher: Blackwell Science Inc Pub. Date: 15 January, 1992 List Price(USD): $55.95 |
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Title: Biological Thermodynamics by Donald T. Haynie ISBN: 0521795494 Publisher: Cambridge University Press Pub. Date: 01 March, 2001 List Price(USD): $40.00 |
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Title: Brock Biology of Microorganisms (10th Edition) by Michael T. Madigan, John Martinko, Jack Parker ISBN: 0130662712 Publisher: Prentice Hall Pub. Date: 09 May, 2002 List Price(USD): $124.00 |
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