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Cracking The Genome: Inside The Race To Unlock Human Dna

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Title: Cracking The Genome: Inside The Race To Unlock Human Dna
by Kevin Davies
ISBN: 0-7432-0479-4
Publisher: Free Press
Pub. Date: 05 January, 2001
Format: Hardcover
Volumes: 1
List Price(USD): $25.00
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Average Customer Rating: 4.36 (11 reviews)

Customer Reviews

Rating: 5
Summary: One of the most important stories of our time. A must-read
Comment: Although science is not everyone's favorite subject, the story of the sequencing of the human genome is of importance to every person on the planet.

The story of the Human Genome Project itself, which is an illustration of how the private sector can succeed where government funded projects have difficulties, is interesting in itself. Even outside of the medical and ethical implications, this story is worth reading for that information alone.

But where this book really provides important food for thought is in the medical and ethical arena. It is now possible to find the location and coding for diseases and potential diseases using this information. How will we use this information? To create cures for devastating degenerative diseases like Huntington's, to find cures for the incurable? Or will we use it to deny medical care to people deemed potential insurance risks.

One thing that came out of the study was the surprising small number of genes that comprise the genome--one third the number that had long been predicted. Clearly, the genome is an instruction set, and the blueprints to build a human, and the errors that create disease, are written in how the genes are interpreted by the biological mechanism.

How we should utilize this information, for good or evil, in years to come will surely be some of the most controversial and important discussions we will have. This book is an excellent place to start in order to understand the basis of this world-shaking achievement.

Rating: 5
Summary: Highly Recommended!
Comment: Ken Davies has written an informed observer's account of the passionate race to solve what some believe to be the most profound scientific riddle of our era: decoding the human genome. His book is an undertaking of ambitious scope: He aims to paint the personalities in all their human colors and offer an accurate historical account, while also drilling deep enough into the research to do justice to the science. He does a beautiful job of suggesting the profound personal motivations of the two protagonists of the drama, scientists Francis Crick and maverick scientist J. Craig Venter. Short of earning your Ph.D. in molecular science, this may be as close as you ever get to understanding what the hoopla was really all about. We [...] recommend Davies' book as a must for savvy thinkers in the biotech business, and an enlightening read for the rest of us mere (genetically flawed) mortals.

Rating: 4
Summary: Interesting
Comment: This is not a book that will tell you the specifics of exactly how the genome is being/has been mapped. If that's what you want, get another book. If, however, you are looking for a behind-the-scenes look at the race to crack the genome, this is the book for you. You'll hear stories pertaining to some of the leading scientists in the field. I read it and enjoyed it, but I am a genetics major in college, so I obviously like genetics. I would suggest that you read this only if you are already interested in the subject, otherwise you will be bored.

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