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Title: Fundamentals of Clinical Trials by Lawrence M. Friedman, Curt Furberg, David L. Demets ISBN: 0-387-98586-7 Publisher: Springer Verlag Pub. Date: November, 1998 Format: Paperback Volumes: 1 List Price(USD): $62.95 |
Average Customer Rating: 4 (4 reviews)
Rating: 4
Summary: CONCISE MULTIDISCIPLINARY APPROACH
Comment: The fact that this book was designed for researchers, who are involved in experimental (clinical) trials, makes the basic knowledge of statistics essential.
Using an interactive multidisciplinary approach to investigation, this handbook embraced all aspects clinical and paraclinical survey. It is very easy-to-follow, and divulges its methodology in concise manner. "Fundamentals of Clinical Trials" is one book that will help alleviate the rigorous chores of epidemiologists. However, an advanced or versatile researcher may complain that some of the information in it are too summarized.
Rating: 4
Summary: Good intro textbook
Comment: I used this book for a class that I took last semester on clinical trial.
The authors do a good job of giving a good overview of the topics of interest, in particular: sample size calculation, use of DSMBs, trial design, choice of endpoints, randomization and issues in data analysis.
The chapters on sample size estimation and use of safety monitoring boards are quite heavy on the statistics. If you've never had an intro class in statistics, then these chapters may be way over your head.
There are a few topics that the authors didn't cover so well that I thought should have been more prominent: Choice of primary endpoints in FDA trials, general requirements of the FDA and regulatory information in general, the calculations of meta-analyses.
Overall I am quite happy with this book and will keep it on my shelf as a good reference.
Rating: 4
Summary: A great introduction to clinical trials
Comment: This book is a very good place to start for those who want to learn about the design and analysis of clinical trials. However there is a heavy emphasis on statistics - a basic knowledge of stats is essential.
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Title: Clinical Trials: A Methodologic Perspective by Steven Piantadosi ISBN: 0471163937 Publisher: Wiley-Interscience Pub. Date: 07 April, 1997 List Price(USD): $115.00 |
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Title: A Manager's Guide to the Design and Conduct of Clinical Trials by Phillip I. Good ISBN: 0471226157 Publisher: Wiley-Liss Pub. Date: 08 August, 2002 List Price(USD): $69.95 |
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Title: Dictionary for Clinical Trials by Simon Day ISBN: 0471985961 Publisher: John Wiley & Sons Pub. Date: 27 July, 1999 List Price(USD): $43.50 |
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Title: Human Trials: Scientists, Investors, and Patients in the Quest for a Cure by Susan Quinn ISBN: 0738206776 Publisher: Perseus Publishing Pub. Date: May, 2002 List Price(USD): $17.00 |
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Title: Designing Clinical Research: An Epidemiologic Approach by Stephen B. Hulley, Steven R. Cummings, Warren S. Browner, Deborah Grady, Norman Hearst, Thomas B. Newman ISBN: 0781722187 Publisher: Lippincott Williams & Wilkins Publishers Pub. Date: 15 January, 2001 List Price(USD): $49.95 |
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