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Mass Spectrometry for Biotechnology

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Title: Mass Spectrometry for Biotechnology
by Gary Siuzdak
ISBN: 0-12-647471-0
Publisher: Academic Press
Pub. Date: 01 March, 1996
Format: Paperback
Volumes: 1
List Price(USD): $50.95
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Average Customer Rating: 4.6 (10 reviews)

Customer Reviews

Rating: 5
Summary: a good beginner reference
Comment: This is an excellent book for the mass spectrometry novice who wants to get a quick understanding of the necessary basics. As mass spec goes mainstream with the genomics and proteomics world, guidebooks like this will become very useful also for qualifying peoples' expectations of the technology. This is a good book also for teachers and students who may not want to get into the deep details but would like to get a good overview of what the art and science of mass spec is about. The book is well-balanced between the technical instrumentation background and discussion of actual applications and types of experiments. The work is fluently written and easy to digest. I run a small mass spec analytical group and have lent this book to several of my colleagues who just "wanted to get an idea" of what I do. They were all very happy with this text. I have used the book as a reference several times in preparation of more general overview talks.

Rating: 2
Summary: REVIEW
Comment: Siuzdak has written a useful book for the novice or a student without a background in biological mass spectrometry. The book's small size and concise treatise, however, gives rise to many trite and overly simplistic explanations of aspects of the field and some errors. Consider, for example, page 37 that describes that a limitation of magnetic mass analyzers is their relatively "low" resolution. This is contradicted in Table 2.1 where a correct representation of the resolution is made. Also on page, Siuzdak describes the "physics behind" ion trap and conventional quadrupole analyzers as being "similar" when ion motion and dynamics in each analyzer is quite different. A textbook to be read with caution!

Rating: 4
Summary: Should be on any biotechnology practicioner's shelf
Comment: I love this book. I spent years selling GC-MS and LC-MS, then worked on software applications. But coming from a biology background, I appreciated the simple yet thorough introduction in Siuzdak's text for the applications commonly used in biotechnology. This is an excellent, well-written introductory text. I recommend it highly.

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